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IIT Guwahati Develops Revolutionary Fluorescent Sensor for Detecting Cyanide in Water and Human Cells

Innovative "Turn-On" Technology Shows Promise for Environmental Safety, Medical Applications, and Forensic Investigations

Assam Front by Assam Front
May 19, 2025
in Education, Guwahati
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Scientists at the Indian Institute of Technology (IIT) Guwahati have developed a revolutionary fluorescent sensor capable of detecting cyanide in both water sources and human cells, representing a significant leap forward in chemical detection technology.

The innovative sensor, which operates using ultraviolet light, demonstrates exceptional sensitivity and efficiency in identifying the presence of cyanide—a lethal compound that poses serious risks to human health and the environment. When exposed to cyanide, the sensor produces a distinctive color change and emits bright fluorescence, enabling rapid and clear detection.

What sets this new technology apart from conventional detection methods is its “turn-on” response mechanism. Unlike traditional approaches that may produce ambiguous results or false negatives, this sensor becomes actively fluorescent in the presence of cyanide, dramatically improving detection clarity and reliability.

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The research team has successfully tested the sensor in real-world scenarios, confirming its effectiveness in river water samples and breast cancer cells. This versatility makes it an invaluable tool across multiple fields, including environmental monitoring, forensic science, and potentially medical diagnostics.

The implications for public health and safety are substantial. Cyanide, even in small quantities, can cause serious health issues or death. Industrial processes such as gold mining, electroplating, and certain manufacturing operations can release cyanide into waterways, creating environmental hazards. This sensor could provide crucial early detection capabilities to prevent contamination incidents.

“The ability to rapidly detect cyanide in various matrices is essential for preventing exposure to this lethal compound,” said a representative from the research team. “Our sensor’s high sensitivity and clear visual response make it particularly valuable in time-sensitive situations.”

Beyond its immediate applications in water safety, the technology shows promise for forensic investigations where cyanide poisoning is suspected. The sensor’s ability to detect cyanide in cellular environments could aid in determining cause of death or exposure in suspicious cases.

The IIT Guwahati team is now working on developing a simple detection kit based on this technology, which would make the innovation accessible for broader applications. This would potentially allow for field testing without specialized laboratory equipment, enabling more widespread monitoring of water sources and industrial outputs.

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